Home About NCP People Facilities Services Instruments Events & Workshops Contact Us
News & Updates
Services Offered:

1) 2D Gel Electrophoresis

2) LC MS/MS  more
Other Services  more

Dr. Zehra Manzoor

Research Interests:

Comparative proteomics, biomarker identification and drug induced modifications in Breast, liver and oral cancer tissues and cell lines. This includes cell culture, protein extraction, protein characterization, 2DE and mass spectrometry. Role of glycation and glycoxidation in cataract formation. Function of antioxidant enzymes and their expression in lens opacity. Identification of taxon specific lens crystallins.


Zohaib, M., Ansari, S.H., Hashim, Z., Shamsi, T.S., Zarina, S. Serum Paraoxonase activity and Malondialdehyde serum levels remain unaffected in response to Hydroxyurea therapy in b-thalassemia patients. J. Clinic. Pharmacol., (accepted)
Ilyas, A., Hashim, Z. Zarina, S. Effects of 5-azacytidine and alendronate on a hepatocellular carcinoma cell line: a proteomics perspective. Molecular and Cellular Biochemistry 405:53-61
Atta, A, Ilyas, A, Hashim, Z, Ahmed A and Zarina, S. Lactate Dehydrogenase Like Crystallin: A Potentially Protective Shield for Indian Spiny-Tailed Lizard (Uromastyx hardwickii) Lens Against Environmental Stress? Protein J DOI 10.1007/s10930-014-9543-4
Ilyas, A., Hashim, Z., Naeem, N., Haneef, K. and Zarina, S. The Effect of Alendronate on Proteome of Hepatocellular Carcinoma Cell Lines. International Journal of proteomics 2014:9 pages.
Malik, U.U, Siddiqui, IA., Hashim, Z. and Zarina, S. Measurement of Serum Paraoxonase Activity and MDA levels in patients suffering with Oral Squamous Cell Carcinoma. Clin Chem acta 430: 38-42.
Hashim, Z. and Zarina, S. Osmotic stress induced oxidative damage: Possible mechanism of cataract formation in diabetes. Journal of Diabetes and Its Complications 2012; 26: 275-279.
Hashim, Z and Zarina, S., Advanced Glycation End Products in diabetic and non-diabetic human subjects suffering from cataract. AGE 33(3) 377-84.
Hashim, Z., Ilyas A., Saleem A., Salim A., Zarina S. "Expression and activity of paraoxonase 1 in human cataractous lens tissue". Free Radic. Biol.Med. 46; 1089-1095.
Hashim Z. and Zarina S. "Assessment of Paraoxonase activity and lipid peroxidation levels in diabetic and senile subjects suffering from cataract". Clin. Biochem. 40; 705-709.
Hashim Z. and Zarina S. "Antioxidant Markers in human senile and diabetic cataractous lenses". J.Coll. Physicians Surg.Pak. 16; 637-640.